Absence of freedom.
Extended or permanent immobility can have severe detrimental ramifications, both physically and emotionally. Among other musculoskeletal effects, muscles atrophy, resulting in loss of strength and endurance, soft tissue integrity diminishes and bone density decreases. (nih.org) Those experiencing extended or permanent immobility may suffer from apathy, reduced quality and quantity of sleep, isolation, frustration and depression, attributed to profound loss of freedom and reduced quality of life.
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